Targeting stem cells suggests way to cure leukemia, mice study shows

Canadian scientists are investigating a novel way of treating a deadly form of leukemia: By targeting the stem cells that allow the cancer to return after chemotherapy has resulted in apparent remission.

Using an experimental drug, researchers at Princess Margaret Hospital in Toronto were able to cure some mice transplanted with the human form of acute myeloid leukemia (AML). The discovery offers promise that the drug could have the same effect in humans with the disease.

Read more about this at the Source:  Yahoo News Canada

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An Aplastic Anemia Cluster in Oregon.

Last February, doctors diagnosed Chuck and Jacqueline Roberts' young daughter, Victoria, with a rare and life-threatening bone marrow disease, aplastic anemia.

Since then, the Robertses say, they have heard of five other cases in Columbia County, where they live, or across the river in Washington's Cowlitz County.

To the couple, six cases in counties with 150,000 residents combined looks suspicious. But is it? Is it just bad luck? Or is something, perhaps a pollutant, causing illness in the area?

Oregon and Washington officials are tackling those questions as they try to figure out whether Victoria, 7, is part of a disease cluster. So far, they have no proof of a cluster. But workers from seven agencies in two states have spent weeks gathering initial information, including climate data from a Kalama, Wash., plant that legally emits tons of benzene, a chemical that can damage the blood of people exposed to large enough amounts. This week, investigators will share their data and discuss whether there is enough suspicion to push ahead.

You can read the entire article here... www.oregonlive.com

Here is a description of Aplastic Anemia from the article.

In aplastic anemia, a person's bone marrow loses the ability to make blood cells that stop bleeding, battle infections and move oxygen through the body. In the United States, an estimated 200 to 1,800 new cases are found each year. Many things can cause the disease: genetic flaws, radiation, some drugs, chemicals such as benzene, even pregnancy. Most commonly, something spurs the body's immune system to attack the marrow, said Dr. Grover Bagby, an aplastic anemia expert at Oregon Health & Science University. But in most cases, no root cause is found.

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